Multimarker scores of Th1 and Th2 immune cellular profiles in peripheral blood predict response and immune related toxicity with CTLA4 blockade and IFNα in melanoma

Neoadjuvant therapy with ipilimumab in combination with high dose IFNα was evaluated in patients with locally/regionally advanced melanoma in a previously reported clinical trial [NCT01608594]. In this study, peripheral immune cell profiling was performed in order to investigate the underlying mecha...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Khunger, Arjun, Sarikonda, Ghanashyam, Tsau, Jennifer, Pahuja, Anil, Alfonso, Zeni, Gao, Jane, Laing, Christian, Vaupel, Christine, Dakappagari, Naveen, Tarhini, Ahmad A.
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2021
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810775/
https://ncbi.nlm.nih.gov/pubmed/33450703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101014
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