Immune inhibitory function of bovine CTLA-4 and the effects of its blockade in IFN-γ production

BACKGROUND: Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is known as an immune inhibitory receptor that is expressed on activated effector T cells and regulatory T cells. When CTLA-4 binds to CD80 or CD86, immunoinhibitory signals are transmitted to retain a homeostasis of the immune response. Recent s...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Watari, Kei, Konnai, Satoru, Maekawa, Naoya, Okagawa, Tomohiro, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820917/
https://ncbi.nlm.nih.gov/pubmed/31665022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-2082-7
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