Expression of PD-L1 on Canine Tumor Cells and Enhancement of IFN-γ Production from Tumor-Infiltrating Cells by PD-L1 Blockade

Programmed death 1 (PD-1), an immunoinhibitory receptor, and programmed death ligand 1 (PD-L1), its ligand, together induce the “exhausted” status in antigen-specific lymphocytes and are thus involved in the immune evasion of tumor cells. In this study, canine PD-1 and PD-L1 were molecularly charact...

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Autors principals: Maekawa, Naoya, Konnai, Satoru, Ikebuchi, Ryoyo, Okagawa, Tomohiro, Adachi, Mami, Takagi, Satoshi, Kagawa, Yumiko, Nakajima, Chie, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051644/
https://ncbi.nlm.nih.gov/pubmed/24915569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098415
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