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A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics

Antibiotics are failing fast, and the development pipeline remains alarmingly dry. New drug research and development is being urged by world health officials, with new antibacterials against multidrug-resistant Gram-negative pathogens as the highest priority. Antivirulence drugs, which inhibit bacte...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Verderosa, Anthony D., Dhouib, Rabeb, Hong, Yaoqin, Anderson, Taylah K., Heras, Begoña, Totsika, Makrina
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810732/
https://ncbi.nlm.nih.gov/pubmed/33452354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81007-y
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