Nogo-66 promotes β-amyloid protein secretion via NgR/ROCK-dependent BACE1 activation

The generation of β-amyloid protein (Aβ) is considered a key step in the pathogenesis of Alzheimer's disease (AD) and the regulation of its production is an important therapeutic strategy. It was hypothesized in the present study that Nogo-A may be involved in AD and may regulate the generation...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Xie, Qing-Qing, Feng, Xiao, Huang, Yi-Yun, Fang, Nian, Yi, Hua, Wang, Zi-Jian, Cao, Qiao-Yu, Lou, Guo-Feng, Pan, Jun-Ping, Hu, Yang, Li, Fang-Cheng, Zheng, Qing, Xiao, Fei
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809900/
https://ncbi.nlm.nih.gov/pubmed/33495810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.11827
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