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Nogo-66 promotes β-amyloid protein secretion via NgR/ROCK-dependent BACE1 activation
The generation of β-amyloid protein (Aβ) is considered a key step in the pathogenesis of Alzheimer's disease (AD) and the regulation of its production is an important therapeutic strategy. It was hypothesized in the present study that Nogo-A may be involved in AD and may regulate the generation...
Kaydedildi:
| Yayımlandı: | Mol Med Rep |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
D.A. Spandidos
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809900/ https://ncbi.nlm.nih.gov/pubmed/33495810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.11827 |
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