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No Nogo66- and NgR-Mediated Inhibition of Regenerating Axons in the Zebrafish Optic Nerve

In contrast to mammals, lesioned axons in the zebrafish (ZF) optic nerve regenerate and restore vision. This correlates with the absence of the NogoA-specific N-terminal domains from the ZF nogo/rtn-4 (reticulon-4) gene that inhibits regeneration in mammals. However, mammalian nogo/rtn-4 carries a s...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Abdesselem, Houari, Shypitsyna, Aleksandra, Solis, Gonzalo P., Bodrikov, Vsevolod, Stuermer, Claudia A. O.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666099/
https://ncbi.nlm.nih.gov/pubmed/20007473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3561-09.2009
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