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No Nogo66- and NgR-Mediated Inhibition of Regenerating Axons in the Zebrafish Optic Nerve

In contrast to mammals, lesioned axons in the zebrafish (ZF) optic nerve regenerate and restore vision. This correlates with the absence of the NogoA-specific N-terminal domains from the ZF nogo/rtn-4 (reticulon-4) gene that inhibits regeneration in mammals. However, mammalian nogo/rtn-4 carries a s...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Abdesselem, Houari, Shypitsyna, Aleksandra, Solis, Gonzalo P., Bodrikov, Vsevolod, Stuermer, Claudia A. O.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666099/
https://ncbi.nlm.nih.gov/pubmed/20007473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3561-09.2009
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