Cell softness regulates tumorigenicity and stemness of cancer cells

Identifying and sorting highly tumorigenic and metastatic tumor cells from a heterogeneous cell population is a daunting challenge. Here, we show that microfluidic devices can be used to sort marker‐based heterogeneous cancer stem cells (CSC) into mechanically stiff and soft subpopulations. The isol...

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Foilsithe in:EMBO J
Main Authors: Lv, Jiadi, Liu, Yaoping, Cheng, Feiran, Li, Jiping, Zhou, Yabo, Zhang, Tianzhen, Zhou, Nannan, Li, Cong, Wang, Zhenfeng, Ma, Longfei, Liu, Mengyu, Zhu, Qiang, Liu, Xiaohan, Tang, Ke, Ma, Jingwei, Zhang, Huafeng, Xie, Jing, Fang, Yi, Zhang, Haizeng, Wang, Ning, Liu, Yuying, Huang, Bo
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809788/
https://ncbi.nlm.nih.gov/pubmed/33274785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106123
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