Macrophages reprogrammed by lung cancer microparticles promote tumor development via release of IL-1β

Despite their mutual antagonism, inflammation and immunosuppression coexist in tumor microenvironments due to tumor and immune cell interactions, but the underlying mechanism remains unclear. Previously, we showed that tumor cell-derived microparticles induce an M2 phenotype characterized by immunos...

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Veröffentlicht in:Cell Mol Immunol
Hauptverfasser: Chen, Jie, Sun, Weiwei, Zhang, Huafeng, Ma, Jingwei, Xu, Pingwei, Yu, Yuandong, Fang, Haiqing, Zhou, Li, Lv, Jiadi, Xie, Jing, Liu, Yuying, Tang, Ke, Huang, Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784894/
https://ncbi.nlm.nih.gov/pubmed/31649305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0313-2
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