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Prioritizing transcriptional factors in gene regulatory networks with PageRank
Biological states are controlled by orchestrated transcriptional factors (TFs) within gene regulatory networks. Here we show TFs responsible for the dynamic changes of biological states can be prioritized with temporal PageRank. We further show such TF prioritization can be extended by integrating g...
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| Pubblicato in: | iScience |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809505/ https://ncbi.nlm.nih.gov/pubmed/33490923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.102017 |
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