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Changes on proteomic and metabolomic profile in serum of mice induced by chronic exposure to tramadol

Tramadol is an opioid used as an analgesic for treating moderate or severe pain. The long-term use of tramadol can induce several adverse effects. The toxicological mechanism of tramadol abuse is unclear. Limited literature available indicates the change of proteomic profile after chronic exposure t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jiang, Shukun, Liu, Guojie, Yuan, Huiya, Xu, Enyu, Xia, Wei, Zhang, Xiaoyu, Liu, Junting, Gao, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809287/
https://ncbi.nlm.nih.gov/pubmed/33446901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81109-7
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