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Toxicology of paraquat and pharmacology of the protective effect of 5-hydroxy-1-methylhydantoin on lung injury caused by paraquat based on metabolomics

Paraquat (PQ) is a non-selective herbicide and is exceedingly toxic to humans. The mechanism of PQ toxicity is very complex and has not been clearly defined. There is no specific antidote for PQ poisoning. 5-hydroxy-1-methylhydantoin (HMH) is an intrinsic antioxidant and can protect against renal da...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Gao, Lina, Yuan, Huiya, Xu, Enyu, Liu, Junting
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000692/
https://ncbi.nlm.nih.gov/pubmed/32019966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58599-y
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