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Mutations of folC cause increased susceptibility to sulfamethoxazole in Mycobacterium tuberculosis

Previous studies showed that mutation of folC caused decreased expression of the dihydropteroate synthase encoding gene folP2 in Mycobacterium tuberculosis (M. tuberculosis). We speculated that mutation of folC in M. tuberculosis might affect the susceptibility to sulfamethoxazole (SMX). To prove th...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Wang, Ruiqi, Li, Kun, Yu, Jifang, Deng, Jiaoyu, Chen, Yaokai
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809127/
https://ncbi.nlm.nih.gov/pubmed/33446754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80213-4
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