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Mutations of folC cause increased susceptibility to sulfamethoxazole in Mycobacterium tuberculosis

Previous studies showed that mutation of folC caused decreased expression of the dihydropteroate synthase encoding gene folP2 in Mycobacterium tuberculosis (M. tuberculosis). We speculated that mutation of folC in M. tuberculosis might affect the susceptibility to sulfamethoxazole (SMX). To prove th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Ruiqi, Li, Kun, Yu, Jifang, Deng, Jiaoyu, Chen, Yaokai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809127/
https://ncbi.nlm.nih.gov/pubmed/33446754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80213-4
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