Prolactin receptor-driven combined luminal and epithelial differentiation in breast cancer restricts plasticity, stemness, tumorigenesis and metastasis

Dedifferentiation increased cellular plasticity and stemness are established derivers of tumor heterogeneity, metastasis and therapeutic failure resulting in incurable cancers. Therefore, it is essential to decipher pro/forward-differentiation mechanisms in cancer that may serve as therapeutic targe...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Shams, Anwar, Binothman, Najat, Boudreault, Julien, Wang, Ni, Shams, Fuad, Hamam, Dana, Tian, Jun, Moamer, Alaa, Dai, Meiou, Lebrun, Jean-Jacques, Ali, Suhad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809050/
https://ncbi.nlm.nih.gov/pubmed/33446633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00297-5
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