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Prolactin receptor-driven combined luminal and epithelial differentiation in breast cancer restricts plasticity, stemness, tumorigenesis and metastasis

Dedifferentiation increased cellular plasticity and stemness are established derivers of tumor heterogeneity, metastasis and therapeutic failure resulting in incurable cancers. Therefore, it is essential to decipher pro/forward-differentiation mechanisms in cancer that may serve as therapeutic targe...

詳細記述

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書誌詳細
出版年:Oncogenesis
主要な著者: Shams, Anwar, Binothman, Najat, Boudreault, Julien, Wang, Ni, Shams, Fuad, Hamam, Dana, Tian, Jun, Moamer, Alaa, Dai, Meiou, Lebrun, Jean-Jacques, Ali, Suhad
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809050/
https://ncbi.nlm.nih.gov/pubmed/33446633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00297-5
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