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Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer

Human epidermal growth factor receptor 2 (HER2)-amplified breast cancers are treated using targeted antibodies and kinase inhibitors, but resistance to these therapies leads to systemic tumor recurrence of metastatic disease. Herein, we conducted gene expression analyses of HER2 kinase inhibitor-res...

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Podrobná bibliografie
Vydáno v:Oncogene
Hlavní autoři: Abdullah, Ammara, Akhand, Saeed Salehin, Paez, Juan Sebastian Paez, Brown, Wells, Pan, Li, Libring, Sarah, Badamy, Michael, Dykuizen, Emily, Solorio, Luis, Andy Tao, W., Wendt, Michael K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808937/
https://ncbi.nlm.nih.gov/pubmed/33128042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01530-6
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