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Pharmacological inhibition of FGFR modulates the metastatic immune microenvironment and promotes response to immune checkpoint blockade

The effectiveness of immunotherapy as a treatment for metastatic breast cancer is limited due to low numbers of infiltrating lymphocytes in metastatic lesions. Herein, we demonstrated that adjuvant therapy using FIIN4, a covalent inhibitor of fibroblast growth factor receptor (FGFR), dramatically de...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Immunol Res
Egile Nagusiak: Akhand, Saeed S, Liu, Zian, Purdy, Stephen C., Abdullah, Ammara, Lin, Hang, Cresswell, Gregory M., Ratliff, Timothy L., Wendt, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710538/
https://ncbi.nlm.nih.gov/pubmed/33093218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-20-0235
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