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Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer

Human epidermal growth factor receptor 2 (HER2)-amplified breast cancers are treated using targeted antibodies and kinase inhibitors, but resistance to these therapies leads to systemic tumor recurrence of metastatic disease. Herein, we conducted gene expression analyses of HER2 kinase inhibitor-res...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Abdullah, Ammara, Akhand, Saeed Salehin, Paez, Juan Sebastian Paez, Brown, Wells, Pan, Li, Libring, Sarah, Badamy, Michael, Dykuizen, Emily, Solorio, Luis, Andy Tao, W., Wendt, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808937/
https://ncbi.nlm.nih.gov/pubmed/33128042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01530-6
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