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Selective Targeting of Nav1.7 with Engineered Spider Venom-Based Peptides

A fundamental mechanism that drives the propagation of electrical signals in the nervous system is the activation of voltage-gated sodium channels. The sodium channel subtype Nav1.7 is critical for the transmission of pain-related signaling, with gain-of-function mutations in Nav1.7 resulting in var...

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Détails bibliographiques
Publié dans:Channels (Austin)
Auteurs principaux: Neff, Robert A., Wickenden, Alan D.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808416/
https://ncbi.nlm.nih.gov/pubmed/33427574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2020.1860382
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