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(−)-Kusunokinin as a Potential Aldose Reductase Inhibitor: Equivalency Observed via AKR1B1 Dynamics Simulation

[Image: see text] (−)-Kusunokinin performed its anticancer potency through CFS1R and AKT pathways. Its ambiguous binding target has, however, hindered the next development phase. Our study thus applied molecular docking and molecular dynamics simulation to predict the protein target from the pathway...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Tanawattanasuntorn, Tanotnon, Thongpanchang, Tienthong, Rungrotmongkol, Thanyada, Hanpaibool, Chonnikan, Graidist, Potchanapond, Tipmanee, Varomyalin
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807751/
https://ncbi.nlm.nih.gov/pubmed/33458512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05102
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