The Fragile X Mental Retardation Protein Regulates RIPK1 and Colorectal Cancer Resistance to Necroptosis

BACKGROUND & AIMS: The fragile X mental retardation protein (FMRP) affects multiple steps of the mRNA metabolism during brain development and in different neoplastic processes. However, the contribution of FMRP in colon carcinogenesis has not been investigated. METHODS: FMR1 mRNA transcript and...

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Bibliographic Details
Published in:Cell Mol Gastroenterol Hepatol
Main Authors: Di Grazia, Antonio, Marafini, Irene, Pedini, Giorgia, Di Fusco, Davide, Laudisi, Federica, Dinallo, Vincenzo, Rosina, Eleonora, Stolfi, Carmine, Franzè, Eleonora, Sileri, Pierpaolo, Sica, Giuseppe, Monteleone, Giovanni, Bagni, Claudia, Monteleone, Ivan
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806864/
https://ncbi.nlm.nih.gov/pubmed/33091622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.10.009
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