ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels

Pannexin 1 (Panx1) is a membrane channel implicated in numerous physiological and pathophysiological processes via its ability to support release of ATP and other cellular metabolites for local intercellular signaling. However, to date, there has been no direct demonstration of large molecule permea...

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Pubblicato in:eLife
Autori principali: Narahari, Adishesh K, Kreutzberger, Alex JB, Gaete, Pablo S, Chiu, Yu-Hsin, Leonhardt, Susan A, Medina, Christopher B, Jin, Xueyao, Oleniacz, Patrycja W, Kiessling, Volker, Barrett, Paula Q, Ravichandran, Kodi S, Yeager, Mark, Contreras, Jorge E, Tamm, Lukas K, Bayliss, Douglas A
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2021
Soggetti:
Structural Biology and Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806264/
https://ncbi.nlm.nih.gov/pubmed/33410749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64787
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