ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels

Pannexin 1 (Panx1) is a membrane channel implicated in numerous physiological and pathophysiological processes via its ability to support release of ATP and other cellular metabolites for local intercellular signaling. However, to date, there has been no direct demonstration of large molecule permea...

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Vydáno v:eLife
Hlavní autoři: Narahari, Adishesh K, Kreutzberger, Alex JB, Gaete, Pablo S, Chiu, Yu-Hsin, Leonhardt, Susan A, Medina, Christopher B, Jin, Xueyao, Oleniacz, Patrycja W, Kiessling, Volker, Barrett, Paula Q, Ravichandran, Kodi S, Yeager, Mark, Contreras, Jorge E, Tamm, Lukas K, Bayliss, Douglas A
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2021
Témata:
Structural Biology and Molecular Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806264/
https://ncbi.nlm.nih.gov/pubmed/33410749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64787
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