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Cytosine methylation of mitochondrial DNA at CpG sequences impacts Transcription Factor A DNA binding and transcription
In eukaryotes, cytosine methylation of nuclear DNA at CpG sequences ((5m)CpG) regulates epigenetic inheritance through alterations in chromatin structure. However, mitochondria lack nucleosomal chromatin, therefore the molecular mechanisms by which (5m)CpG influences mitochondria must be different a...
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| Udgivet i: | Biochim Biophys Acta Gene Regul Mech |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7806247/ https://ncbi.nlm.nih.gov/pubmed/30807854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2019.01.006 |
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