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CpG methylation patterns of human mitochondrial DNA

The epigenetic modification of mitochondrial DNA (mtDNA) is still in controversy. To clarify this point, we applied the gold standard method for DNA methylation, bisulfite pyrosequencing, to examine human mtDNA methylation status. Before bisulfite conversion, BamHI was used to digest DNA to open the...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Liu, Baojing, Du, Qingqing, Chen, Lu, Fu, Guangping, Li, Shujin, Fu, Lihong, Zhang, Xiaojing, Ma, Chunling, Bin, Cong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800444/
https://ncbi.nlm.nih.gov/pubmed/26996456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23421
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