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CpG methylation patterns of human mitochondrial DNA

The epigenetic modification of mitochondrial DNA (mtDNA) is still in controversy. To clarify this point, we applied the gold standard method for DNA methylation, bisulfite pyrosequencing, to examine human mtDNA methylation status. Before bisulfite conversion, BamHI was used to digest DNA to open the...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Liu, Baojing, Du, Qingqing, Chen, Lu, Fu, Guangping, Li, Shujin, Fu, Lihong, Zhang, Xiaojing, Ma, Chunling, Bin, Cong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800444/
https://ncbi.nlm.nih.gov/pubmed/26996456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23421
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