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Cytosine methylation of mitochondrial DNA at CpG sequences impacts Transcription Factor A DNA binding and transcription

In eukaryotes, cytosine methylation of nuclear DNA at CpG sequences ((5m)CpG) regulates epigenetic inheritance through alterations in chromatin structure. However, mitochondria lack nucleosomal chromatin, therefore the molecular mechanisms by which (5m)CpG influences mitochondria must be different a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochim Biophys Acta Gene Regul Mech
Prif Awduron: Dostal, Vishantie, Churchill, Mair E.A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806247/
https://ncbi.nlm.nih.gov/pubmed/30807854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2019.01.006
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