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Cytosine methylation of mitochondrial DNA at CpG sequences impacts Transcription Factor A DNA binding and transcription

In eukaryotes, cytosine methylation of nuclear DNA at CpG sequences ((5m)CpG) regulates epigenetic inheritance through alterations in chromatin structure. However, mitochondria lack nucleosomal chromatin, therefore the molecular mechanisms by which (5m)CpG influences mitochondria must be different a...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Gene Regul Mech
Main Authors: Dostal, Vishantie, Churchill, Mair E.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806247/
https://ncbi.nlm.nih.gov/pubmed/30807854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2019.01.006
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