O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease

The dopamine system in the midbrain is essential for volitional movement, action selection, and reward-related learning. Despite its versatile roles, it contains only a small set of neurons in the brainstem. These dopamine neurons are especially susceptible to Parkinson’s disease and prematurely deg...

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Veröffentlicht in:Brain
Hauptverfasser: Lee, Byeong Eun, Kim, Hye Yun, Kim, Hyun-Jin, Jeong, Hyeongsun, Kim, Byung-Gyu, Lee, Ha-Eun, Lee, Jieun, Kim, Han Byeol, Lee, Seung Eun, Yang, Yong Ryoul, Yi, Eugene C, Hanover, John A, Myung, Kyungjae, Suh, Pann-Ghill, Kwon, Taejoon, Kim, Jae-Ick
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805798/
https://ncbi.nlm.nih.gov/pubmed/33300544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa320
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