Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex

Human DNA methylation data have been used to develop biomarkers of ageing, referred to as ‘epigenetic clocks’, which have been widely used to identify differences between chronological age and biological age in health and disease including neurodegeneration, dementia and other brain phenotypes. Exis...

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Veröffentlicht in:Brain
Hauptverfasser: Shireby, Gemma L, Davies, Jonathan P, Francis, Paul T, Burrage, Joe, Walker, Emma M, Neilson, Grant W A, Dahir, Aisha, Thomas, Alan J, Love, Seth, Smith, Rebecca G, Lunnon, Katie, Kumari, Meena, Schalkwyk, Leonard C, Morgan, Kevin, Brookes, Keeley, Hannon, Eilis, Mill, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805794/
https://ncbi.nlm.nih.gov/pubmed/33300551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa334
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