A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry ()

Although men of African ancestry have a high risk of prostate cancer (PCa), no genes or mutations have been identified that contribute to familial clustering of PCa in this population. We investigated whether the African ancestry–specific PCa risk variant at 8q24, rs72725854, is enriched in men with...

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Publicado no:Eur Urol
Main Authors: Darst, Burcu F., Wan, Peggy, Sheng, Xin, Bensen, Jeannette T., Ingles, Sue A., Rybicki, Benjamin A., Nemesure, Barbara, John, Esther M., Fowke, Jay H., Stevens, Victoria L., Berndt, Sonja I., Huff, Chad D., Strom, Sara S., Park, Jong Y., Zheng, Wei, Ostrander, Elaine A., Walsh, Patrick C., Srivastava, Shiv, Carpten, John, Sellers, Thomas A., Yamoah, Kosj, Murphy, Adam B., Sanderson, Maureen, Crawford, Dana C., Gapstur, Susan M., Bush, William S., Aldrich, Melinda C., Cussenot, Olivier, Yeager, Meredith, Petrovics, Gyorgy, Cullen, Jennifer, Neslund-Dudas, Christine, Kittles, Rick A., Xu, Jianfeng, Stern, Mariana C., Kote-Jarai, Zsofia, Govindasami, Koveela, Chokkalingam, Anand P., Multigner, Luc, Parent, Marie-Elise, Menegaux, Florence, Cancel-Tassin, Geraldine, Kibel, Adam S., Klein, Eric A., Goodman, Phyllis J., Drake, Bettina F., Hu, Jennifer J., Clark, Peter E., Blanchet, Pascal, Casey, Graham, Hennis, Anselm J.M., Lubwama, Alexander, Thompson, Ian M., Leach, Robin, Gundell, Susan M., Pooler, Loreall, Xia, Lucy, Mohler, James L., Fontham, Elizabeth T.H., Smith, Gary J., Taylor, Jack A., Eeles, Rosalind A., Brureau, Laurent, Chanock, Stephen J., Watya, Stephen, Stanford, Janet L., Mandal, Diptasri, Isaacs, William B., Cooney, Kathleen, Blot, William J., Conti, David V., Haiman, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805560/
https://ncbi.nlm.nih.gov/pubmed/32409115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2020.04.060
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