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Structural analysis of the chicken FANCM–MHF complex and its stability

FANCM is involved in eukaryotic DNA-damage recognition and activates the Fanconi anemia (FA) pathway through complex formation. MHF is one of the FANCM-associating components and contains a histone-fold DNA-binding domain. Loss of the FANCM–MHF interaction compromises the activation of the FA pathwa...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Ito, Sho, Nishino, Tatsuya
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805551/
https://ncbi.nlm.nih.gov/pubmed/33439149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X20016003
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