The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability

Histone-fold proteins typically assemble in multiprotein complexes to bind duplex DNA. However, one histone-fold complex, MHF, associates with Fanconi anemia (FA) protein FANCM to form a branched DNA remodeling complex that senses and repairs stalled replication forks and activates FA DNA damage res...

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Detalhes bibliográficos
Main Authors: Fox, David, Yan, Zhijiang, Ling, Chen, Zhao, Ye, Lee, Duck-Yeon, Fukagawa, Tatsuo, Yang, Wei, Wang, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011343/
https://ncbi.nlm.nih.gov/pubmed/24699063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.42
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