Chitinase 3-like-1 is a Therapeutic Target That Mediates the Effects of Aging in COVID-19

COVID-19 is caused by the SARS-CoV-2 (SC2) virus and is more prevalent and severe in the elderly and patients with comorbid diseases (CM). Because chitinase 3-like-1 (CHI3L1) is induced during aging and CM, the relationships between CHI3L1 and SC2 were investigated. Here we demonstrate that CHI3L1 i...

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Gepubliceerd in:bioRxiv
Hoofdauteurs: Kamle, Suchitra, Ma, Bing, He, Chuan Hua, Akosman, Bedia, Zhou, Yang, Lee, Chang-Min, El-Deiry, Wafik S., Huntington, Kelsey, Liang, Olin, Machan, Jason T., Kang, Min-Jong, Shin, Hyeon Jun, Mizoguchi, Emiko, Lee, Chun Geun, Elias, Jack A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805436/
https://ncbi.nlm.nih.gov/pubmed/33442679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.05.425478
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