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N-Glycosylation Regulates Chitinase 3–like-1 and IL-13 Ligand Binding to IL-13 Receptor α2
Chitinase 3–like-1 (Chi3l1) and IL-13 are both ligands of IL-13 receptor α2 (IL-13Rα2). The binding of the former activates mitogen-activated protein kinase, AKT, and Wnt/β-catenin signaling, and plays important roles in innate and adaptive immunity, cellular apoptosis, oxidative injury, allergic in...
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| Veröffentlicht in: | Am J Respir Cell Mol Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Thoracic Society
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7462338/ https://ncbi.nlm.nih.gov/pubmed/32402213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0446OC |
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