N-Glycosylation Regulates Chitinase 3–like-1 and IL-13 Ligand Binding to IL-13 Receptor α2

Chitinase 3–like-1 (Chi3l1) and IL-13 are both ligands of IL-13 receptor α2 (IL-13Rα2). The binding of the former activates mitogen-activated protein kinase, AKT, and Wnt/β-catenin signaling, and plays important roles in innate and adaptive immunity, cellular apoptosis, oxidative injury, allergic in...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Cell Mol Biol
Asıl Yazarlar: He, Chuan Hua, Lee, Chun Geun, Ma, Bing, Kamle, Suchitra, Choi, Augustine M. K., Elias, Jack A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2020
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462338/
https://ncbi.nlm.nih.gov/pubmed/32402213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0446OC
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