IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

Recent studies demonstrated that chitinase 3-like-1 (Chi3l1) binds to and signals via IL-13Rα2. However, the mechanism that IL-13Rα2 uses to mediate the effects of Chi3l1 has not been defined. Here, we demonstrate that the membrane protein, TMEM219, is a binding partner of IL-13Rα2 using yeast two-h...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Lee, Chang-Min, He, Chuan Hua, Nour, Adel M., Zhou, Yang, Ma, Bing, Park, Jin Wook, Kim, Kyung Hee, Cruz, Charles Dela, Sharma, Lokesh, Nasr, Mahmoud L., Modis, Yorgo, Lee, Chun Geun, Elias, Jack A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027616/
https://ncbi.nlm.nih.gov/pubmed/27629921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12752
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