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Concizumab: a novel anti-TFPI therapeutic for hemophilia

Concizumab is a novel subcutaneous prophylactic therapy for hemophilia. It is a hemostatic rebalancing agent that binds to the Kunitz-2 domain of tissue factor pathway inhibitor (TFPI), one of the molecules that contributes to downregulation of coagulation thereby preventing TFPI from binding to and...

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Bibliografske podrobnosti
izdano v:Blood Adv
Glavni avtor: Shapiro, Amy D.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805331/
https://ncbi.nlm.nih.gov/pubmed/33570646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001140
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