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Inhibition of Tissue Factor Pathway Inhibitor (TFPI) as a Treatment for Haemophilia: Rationale with Focus on Concizumab

Replacement therapy with missing factor (F) VIII or IX in haemophilia patients for bleed management and preventative treatment or prophylaxis is standard of care. Restoration of thrombin generation through novel mechanisms has become the focus of innovation to overcome limitations imposed by protein...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Drugs
1. Verfasser: Chowdary, Pratima
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013504/
https://ncbi.nlm.nih.gov/pubmed/29845491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-018-0922-6
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