Modulation of IL-6/STAT3 signaling axis in CD4(+)FOXP3(−) T cells represents a potential antitumor mechanism of azacitidine

CD4(+) T cells orchestrate immune responses and are actively engaged in shaping tumor immunity. Signal transducer and activator of transcription (STAT) signaling controls the epigenetic tuning of CD4(+) T-cell differentiation and polarization, and perturbed STAT signaling networks in CD4(+) T cells...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Lamprianidou, Eleftheria, Kordella, Chryssoula, Kazachenka, Anastasiya, Zoulia, Emmanouela, Bernard, Elsa, Filia, Anastasia, Laidou, Stamatia, Garantziotis, Panayiotis, Vassilakopoulos, Theodoros P., Papageorgiou, Sotirios G., Pappa, Vassiliki, Galanopoulos, Athanasios G., Viniou, Nora, Nakou, Evangelia, Kalafati, Lydia, Chatzidimitriou, Anastasia, Kassiotis, George, Papaemmanuil, Elli, Mitroulis, Ioannis, Kotsianidis, Ioannis
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805308/
https://ncbi.nlm.nih.gov/pubmed/33570632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002351
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