Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling

Benign peripheral nerve sheath tumors are the clinical hallmark of Neurofibromatosis Type 1. They account for substantial morbidity and mortality in NF1. Cutaneous (CNF) and plexiform neurofibromas (PNF) share nearly identical histology, but maintain different growth rates and risk of malignant conv...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Epigenetics Chromatin
Autori principali: Grit, Jamie L., Johnson, Benjamin K., Dischinger, Patrick S., J. Essenburg, Curt, Adams, Marie, Campbell, Stacy, Pollard, Kai, Pratilas, Christine A., Triche, Tim J., Graveel, Carrie R., Steensma, Matthew R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805211/
https://ncbi.nlm.nih.gov/pubmed/33436083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00380-6
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi