Nucleoprotein-based ELISA for detection of SARS-COV-2 IgG antibodies: Could an old assay be suitable for serodiagnosis of the new coronavirus?

OBJECTIVES: We evaluated the performance of a nucleoprotein-based enzyme-linked immunosorbent assay (ELISA) for detection of IgG antibodies to SARS-CoV-2. METHODS: The ELISA was based on serum IgG reactivity to a 46-kDa protein derived from the recombinant SARS-CoV2 nucleoprotein. Assay sensitivity...

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書誌詳細
出版年:J Virol Methods
主要な著者: Tozetto-Mendoza, Tania Regina, Kanunfre, Kelly Aparecida, Vilas-Boas, Lucy Santos, Sanchez Espinoza, Evelyn Patricia, Paião, Heuder Gustavo Oliveira, Rocha, Mussya Cisotto, de Paula, Anderson Vicente, de Oliveira, Maura Salaroli, Zampelli, Daniella Bosco, Vieira, José Mauro, Buss, Lewis, Costa, Silvia Figueiredo, Sabino, Ester Cerdeira, Witkin, Steven S., Okay, Thelma Suely, Mendes-Correa, Maria Cassia
フォーマット: Artigo
言語:Inglês
出版事項: Published by Elsevier B.V. 2021
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804377/
https://ncbi.nlm.nih.gov/pubmed/33453299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2021.114064
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