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Nucleoprotein-based ELISA for detection of SARS-COV-2 IgG antibodies: Could an old assay be suitable for serodiagnosis of the new coronavirus?

OBJECTIVES: We evaluated the performance of a nucleoprotein-based enzyme-linked immunosorbent assay (ELISA) for detection of IgG antibodies to SARS-CoV-2. METHODS: The ELISA was based on serum IgG reactivity to a 46-kDa protein derived from the recombinant SARS-CoV2 nucleoprotein. Assay sensitivity...

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Bibliografische gegevens
Gepubliceerd in:J Virol Methods
Hoofdauteurs: Tozetto-Mendoza, Tania Regina, Kanunfre, Kelly Aparecida, Vilas-Boas, Lucy Santos, Sanchez Espinoza, Evelyn Patricia, Paião, Heuder Gustavo Oliveira, Rocha, Mussya Cisotto, de Paula, Anderson Vicente, de Oliveira, Maura Salaroli, Zampelli, Daniella Bosco, Vieira, José Mauro, Buss, Lewis, Costa, Silvia Figueiredo, Sabino, Ester Cerdeira, Witkin, Steven S., Okay, Thelma Suely, Mendes-Correa, Maria Cassia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Published by Elsevier B.V. 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804377/
https://ncbi.nlm.nih.gov/pubmed/33453299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2021.114064
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