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Establishment of a long-term stable β-cell line and its application to analyze the effect of Gcg expression on insulin secretion
A pancreatic β-cell line MIN6 was previously established in our lab from an insulinoma developed in an IT6 transgenic mouse expressing the SV40 T antigen in β-cells. This cell line has been widely used for in vitro analysis of β-cell function, but tends to lose the mature β-cell features, including...
Zapisane w:
| Wydane w: | Sci Rep |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7804151/ https://ncbi.nlm.nih.gov/pubmed/33436850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79992-7 |
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