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Functional Analysis of Novel Candidate Regulators of Insulin Secretion in the MIN6 Mouse Pancreatic β Cell Line

Elucidating the regulation of glucose-stimulated insulin secretion (GSIS) in pancreatic β cells is important for understanding and treating diabetes. The pancreatic β cell line, MIN6, retains GSIS but gradually loses it in long-term culture. The MIN6 subclone, MIN6c4, exhibits well-regulated GSIS ev...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kobayashi, Masaki, Yamato, Eiji, Tanabe, Koji, Tashiro, Fumi, Miyazaki, Satsuki, Miyazaki, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795703/
https://ncbi.nlm.nih.gov/pubmed/26986842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151927
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