A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids

Developing effective drugs for Alzheimer’s disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, we report an efficient, network-based drug-screening platform developed by integrating mathematical modeling and the pathological features of AD w...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Park, Jong-Chan, Jang, So-Yeong, Lee, Dongjoon, Lee, Jeongha, Kang, Uiryong, Chang, Hongjun, Kim, Haeng Jun, Han, Sun-Ho, Seo, Jinsoo, Choi, Murim, Lee, Dong Young, Byun, Min Soo, Yi, Dahyun, Cho, Kwang-Hyun, Mook-Jung, Inhee
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804132/
https://ncbi.nlm.nih.gov/pubmed/33436582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20440-5
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