A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids

Developing effective drugs for Alzheimer’s disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, we report an efficient, network-based drug-screening platform developed by integrating mathematical modeling and the pathological features of AD w...

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Publicat a:Nat Commun
Autors principals: Park, Jong-Chan, Jang, So-Yeong, Lee, Dongjoon, Lee, Jeongha, Kang, Uiryong, Chang, Hongjun, Kim, Haeng Jun, Han, Sun-Ho, Seo, Jinsoo, Choi, Murim, Lee, Dong Young, Byun, Min Soo, Yi, Dahyun, Cho, Kwang-Hyun, Mook-Jung, Inhee
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804132/
https://ncbi.nlm.nih.gov/pubmed/33436582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20440-5
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