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A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids
Developing effective drugs for Alzheimer’s disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, we report an efficient, network-based drug-screening platform developed by integrating mathematical modeling and the pathological features of AD w...
Zapisane w:
| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7804132/ https://ncbi.nlm.nih.gov/pubmed/33436582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20440-5 |
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