Subanesthetic isoflurane abates ROS-activated MAPK/NF-κB signaling to repress ischemia-induced microglia inflammation and brain injury

Isoflurane (ISO) elicits protective effects on ischemia-induced brain injury. We investigated whether sub-anesthetic (0.7%) ISO post-conditioning attenuates the inflammation and apoptosis in oxygen-glucose deprivation (OGD)-insulted co-cultures (microglia and neurons) in vitro and the brain injury o...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Yao, Zhiqiang, Liu, Ningning, Zhu, Xiaoshan, Wang, Ling, Zhao, Yali, Liu, Qinqin, Gao, Chunfang, Li, Juntang
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803578/
https://ncbi.nlm.nih.gov/pubmed/33373319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202349
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