Subanesthetic Isoflurane Reduces Zymosan-Induced Inflammation in Murine Kupffer Cells by Inhibiting ROS-Activated p38 MAPK/NF-κB Signaling

Volatile anesthetic isoflurane (ISO) has immunomodulatory effects. The fungal component zymosan (ZY) induces inflammation through toll-like receptor 2 or dectin-1 signaling. We investigated the molecular actions of subanesthetic (0.7%) ISO against ZY-induced inflammatory activation in murine Kupffer...

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Hauptverfasser: Wang, Hui, Wang, Lei, Li, Nan-lin, Li, Jun-tang, Yu, Feng, Zhao, Ya-li, Wang, Ling, Yi, Jun, Bian, Jie-fang, Chen, Jiang-hao, Yuan, Shi-fang, Wang, Ting, Lv, Yong-gang, Liu, Ning-ning, Zhu, Xiao-shan, Ling, Rui, Yun, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134815/
https://ncbi.nlm.nih.gov/pubmed/25147596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/851692
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