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Sexual dimorphism in aging hematopoiesis: an earlier decline of hematopoietic stem and progenitor cells in male than female mice

Adult hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow (BM) ensuring homeostasis of blood production and immune response throughout life. Sex differences in immunocompetence and mortality are well-documented in humans. However, whether HSPCs behave dimorphically between sexe...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: So, Eui-Young, Jeong, Euy-Myoung, Wu, Keith Q., Dubielecka, Patrycja M., Reginato, Anthony M., Quesenberry, Peter J., Liang, Olin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803521/
https://ncbi.nlm.nih.gov/pubmed/33378745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202167
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